Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

In aquatic invertebrates (D. Magna) the 48-h EC50 value is > 5 mg/L (nominal).

Key value for chemical safety assessment

Additional information

The acute toxicity to aquatic invertebrates was determined in a study according to OECD guideline No 202 and in compliance with GLP criteria (BASF SE, 2015). In this study daphnids (D. magna, 20 per concentration) were exposed to nominal concentrations of 0 (control) and 5 mg/L for 48 hours under semi-static conditions (test medium renewal after 24 hours). The test concentration of 5 mg/L is the experimentally confirmed critical micelle concentration (CMC). Nominal concentrations were analytically verified via analysis of total organic carbon (TOC), measured as NPOC (Non Purgeable Organic Carbon) at the start of the exposure intervals (0 and 24 hours) and at the end of the exposure intervals (24 and 48 hours). The measured TOC concentrations remained within ± 20 % of the nominal. Therefore, effect values are expressed as nominal. Immobilisation was determined in all groups after 24 and 48 h. No immobilization or other signs of toxicity were observed throughout the test. Based on these findings the 48-h EC50 value is determined at > 5 mg/L.