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Diss Factsheets
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EC number: 911-296-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-05-24 to 2017-
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- See below
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 123 (n-octanol/water partition coefficient; slow stirring)
- Deviations:
- yes
- Remarks:
- See below
- Principles of method if other than guideline:
- The water solubility of the test item Reaction mass of dodecyl acrylate and tridecyl acrylate was assessed using a protocol adapted from the flask method (OECD 105) with slow stirring conditions described in the OECD test guideline 123.
Due to the viscous property of the test item, the definitive protocol was adapted from the flask method with slow stirring conditions described in the OECD 123 guideline: test solutions were prepared at a high loading rate of 1 g/L. - GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 16.3 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20.2 °C
- pH:
- >= 5.7 - <= 5.9
- Conclusions:
- The water solubility of the test item Reaction mass of dodecyl acrylate and tridecyl acrylate was assessed using a protocol adapted from the flask method (OECD 105) with slow stirring conditions described in the OECD test guideline 123. The water solubility of Reaction mass of dodecyl acrylate and tridecyl acrylate is 16.3 µg/L.
The test was run at 20.2°C on average (min. 20.2°C, max. 20.3°C). pH values were between 5.7 and 5.9. - Executive summary:
The water solubility of the test item Reaction mass of dodecyl acrylate and tridecyl acrylate was assessed using a protocol adapted from the flask method (OECD 105) with slow stirring conditions described in the OECD test guideline 123.
Due to the viscous property of the test item, the definitive protocol was adapted from the flask method with slow stirring conditions described in the OECD 123 guideline: test solutions were prepared at a high loading rate of 1 g/L.
Results are summarized below (all results are in µg/L):
Time point (hours)
Flask
Mean
Mean of replicates
Difference from previous time point (%)
Overall Mean Measured Test Item
4.5
Replicate 1
NA
NA
Replicate 2
NA
23.5
Replicate 1
15.5
15.5
NA
Replicate 2
15.4
28.5
Replicate 1
16.1
15.5
0.3
Replicate 2
14.9
47.5
Replicate 1
19.4
18.6
20.1
Replicate 2
17.8
52.5
Replicate 1
20.2
19.3
3.8
Replicate 2
18.5
71.5
Replicate 1
17.1
15.9
-18.0
16.3
Replicate 2
14.6
76.5
Replicate 1
18.4
16.3
2.5
Replicate 2
14.1
167.5
Replicate 1
16.6
16.9
3.9
Replicate 2
17.1
The solubility of Reaction mass of dodecyl acrylate and tridecyl acrylate is 16.3 µg/L.
The test was run at 20.2°C on average (min. 20.2°C, max. 20.3°C). pH values were between pH 5.7 and 5.9.
Reference
Preliminary Test
Increasing volumes of ultra-pure water up to 100 mL were added at room temperature to approximately 0.1 g of the sample in a 100 mL glass flask. After each addition of medium, the test solution was unclear and droplets were observed (probably due to the viscous property of the test item):the approximate solubility was thus estimated to be < 1 g/L.
Definitive Test
Based on OECD test guideline 105 specifications, the saturation equilibrium was considered to be reached from time point 71.5h onwards. Indeed, the concentrations measured at the two last sampling times (76.5h and 167.5h) did not differ by more than 15% from the concentrations measured at 71.5h (see table below). The water solubility of the test item was therefore calculated as the mean of the concentrations determined during this period. The value obtained was 16.3 µg/L.
Time point (hours) |
Flask |
Mean |
Mean of replicates |
Difference from previous time point (%) |
Overall Mean Measured Test Item (µg/L) |
|
4.5 |
Replicate 1 |
NA |
NA |
|||
Replicate 2 |
NA |
|||||
23.5 |
Replicate 1 |
15.5 |
15.5 |
NA |
||
Replicate 2 |
15.4 |
|||||
28.5 |
Replicate 1 |
16.1 |
15.5 |
0.3 |
||
Replicate 2 |
14.9 |
|||||
47.5 |
Replicate 1 |
19.4 |
18.6 |
20.1 |
||
Replicate 2 |
17.8 |
|||||
52.5 |
Replicate 1 |
20.2 |
19.3 |
3.8 |
||
Replicate 2 |
18.5 |
|||||
71.5 |
Replicate 1 |
17.1 |
15.9 |
-18.0 |
16.3 |
|
Replicate 2 |
14.6 |
|||||
76.5 |
Replicate 1 |
18.4 |
16.3 |
2.5 |
||
Replicate 2 |
14.1 |
|||||
167.5 |
Replicate 1 |
16.6 |
16.9 |
3.9 |
||
Replicate 2 |
17.1 |
Temperature was monitored during the test and remained between 20.2°C and 20.3°C (mean 20.2).
pH values were between pH 5.7 and 5.9 in all samples.
Description of key information
The water solubility of the test item Reaction mass of dodecyl acrylate and tridecyl acrylate was determined by an experimental study adapted from the flask method (OECD Test Guideline 105) with slow-stirring conditions described in the OECD Test Guideline 123.
The solubility of Reaction mass of dodecyl acrylate and tridecyl acrylate is 16.3 µg/L at 20.2°C (pH between 5.7 and 5.9).
Key value for chemical safety assessment
- Water solubility:
- 16.3 µg/L
- at the temperature of:
- 20.2 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.