Registration Dossier
Registration Dossier
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EC number: 203-678-8 | CAS number: 109-53-5
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets scientific standards
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
- Type of study / information:
- occupational exposure measurements
- Endpoint addressed:
- not applicable
- Principles of method if other than guideline:
- occupational exposure measurements
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Isobutyl vinyl ether
- EC Number:
- 203-678-8
- EC Name:
- Isobutyl vinyl ether
- Cas Number:
- 109-53-5
- Molecular formula:
- C6H12O
- IUPAC Name:
- 1-(ethenyloxy)-2-methylpropane
- Details on test material:
- no details available
Constituent 1
Method
- Ethical approval:
- not specified
- Details on study design:
- no details available
- Exposure assessment:
- measured
- Details on exposure:
- no details available
Results and discussion
- Results:
- Values found for IBVE were on a reduced level due to the lower vapor pressure. 59 analytical values with a range of < 0.004 mg/m³ (0.001 ppm) to 5.0 mg/m³ (1.2 ppm) are available for the years 2000 - 2004. Mean value, 90 % and 95 % percentiles were at 0.26 mg/m³ (0.062 ppm), 0.96 mg/m³ (0.23 ppm), and 1.6 mg/m³ (0.39 ppm), respectively.
Similar to EVE, the higher concentrations were found during barreling. In the processing plants, highest concentrations were measured to be 0.1 and 1.1 mg/m³, respectively.
Applicant's summary and conclusion
- Conclusions:
- Occupational exposure measurements were documented for the years 2000 - 2004. Mean value, 90 % and 95 % percentiles were at 0.26 mg/m³ (0.062 ppm), 0.96 mg/m³ (0.23 ppm), and 1.6 mg/m³ (0.39 ppm), respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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