Registration Dossier

Administrative data

Description of key information

The following studies are available:
Acute oral toxicity in the rat: LD50>2000 mg/kg bodyweight
Acute dermal toxicity to rat: LD50> 5000 mg/kg bodyweight.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
2 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
5 000 mg/kg bw

Additional information

Dibromoneopentyl glycol was found to be not acutely toxic by the neither the oral or the dermal route. The rat oral LD50 > 2000 mg/kg bw. The rat dermal LD50 was >5000 mg/kg bw. The inhalation route is not likely to be a route of exposure due to the low vapour pressure (2 x10-3 Pa) and particle size (D10) higher than 100 microne.

Justification for classification or non-classification

Based upon the high LD50 values for oral and dermal exposure, together with scarce possibility for exposure via inhalation, the substance does not need to be classified for acute toxicity according to Directive 67/548/EEC or Regulation (EC) No 1272/2008.