Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): allyl alcohol
- Substance type: organic
- Physical state: liquid
- Analytical purity: 99%

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Nominal and measured concentrations:
0, 0.32, 0.56, 0.68, 0.82 and 1.0 mg/L [nominal]

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
0.589 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
LC50 (96h) = 0.59 mg/L
Executive summary:

Medaka (Oryzias latipes) were exposed to allyl alcohol under semi-static conditions at nominal concentrations of 0, 0.32, 0.56, 0.68, 0.82, and 1.0 mg/L for 96 hours [OECD TG 203]. Chemical analysis of the old (expired) test solution 24

hours after renewal showed that the measured concentrations ranged from 90 % to 102 % of the nominal test concentrations. The LC50 (96-h) for Medaka was 0.59 mg/L.