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EC number: 946-046-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Study period:
- 16 May 2012 - 19 June 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP-study, no deviation.
- Justification for type of information:
- REPORTING FORMAT FOR THE CATEGORY APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The read across follows Scenario 5 - Qualitatively and quantitatively similar effects are caused by a common compound, which is formed from all category members (as described in the 2017 Read-Across Assessment Framework document).
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
TARGET: Reaction Mass of 4-sulphophthalic acid and 3-sulphophthalic acid (ratio 3:1)
SOURCE: Sulphophthalic acid sodium salts
3. CATEGORY APPROACH JUSTIFICATION
Sulphophthalic acid sodium and ammonium salts are different organic salts of a common acid, sulfophthalic acid. The salts dissociate rapidly in the medium (water) to the common sulphophthalic acid anion and to their different counter ions. The counter ions ammonium and sodium do not influence the solubility and the toxicity of the category members.
4. DATA MATRIX
See Read Across document attached to CSR. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Municipal activated sludge from laboratory wastewater treatment plant fed with municipal sewage and synthetic wastewater.
- Concentration of sludge: 30 mg/l - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Remarks:
- equivalent to 199 mg/L
- Parameter followed for biodegradation estimation:
- DOC removal
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (DOC removal)
- Remarks:
- Test Temperature: 22± 2°C
- Value:
- > 90 - < 100
- Sampling time:
- 28 d
- Results with reference substance:
- - Deviation of degree of biodegradation of the test substance at the end of exposure should be <20%: Yes
- Degree of biodegradation of the reference substance should be >70% DOC after 14 days: Yes (97%)
- Degree of biodegradation in the inhibition control should be >35 % DOC after 14 days: Yes (70%) - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
There are no biodegradation studies on the 4-sulphophthalic acid and 3-sulphophthalic acid reaction mass (read across target substance) and biodegradation information from a dissolved organic carbon (DOC) Die-Away test on the reaction mass of 1,2-Benzenedicarboxylic acid, 4-sulfo-, trisodium salt, 1,2-Benzenedicarboxylic acid, 3-sulfo-, sodium salt (1:3), sodium sulphate (read across source substance) was used for reading across. The DOC values at the respective sampling days were compared to the DOC values determined on day 0 at begin of exposure. At the end of exposure after 28-days the degree of biodegradation was 90-100 % expressed as removal of DOC. The degree of biodegradation was calculated as mean of the values from two test assays at the end of exposure. The sulphophthalic acid sodium salt reaction mass was 90 -100% biodegradable in the DOC Die-Away Test. Based on the determined rate of biodegradation at the end of exposure the read across source substance can be evaluated as readily biodegradable.
Reference
Description of key information
There are no biodegradation studies on the 4-sulphophthalic acid and 3-sulphophthalic acid reaction mass (read across target substance) and biodegradation information from a dissolved organic carbon (DOC) Die-Away test on the reaction mass of 1,2-Benzenedicarboxylic acid, 4-sulfo-, trisodium salt, 1,2-Benzenedicarboxylic acid, 3-sulfo-, sodium salt (1:3), sodium sulphate (read across source substance) was used for reading across purposes. The DOC values at the respective sampling days were compared to the DOC values determined on day 0 at begin of exposure. At the end of exposure after 28-days the degree of biodegradation was 90-100 % expressed as removal of DOC. The degree of biodegradation was calculated as mean of the values from two test assays at the end of exposure. The sulphophthalic acid sodium salt reaction mass was 90 -100% biodegradable in the DOC Die-Away Test. Based on the determined rate of biodegradation at the end of exposure the read across source substance can be evaluated as readily biodegradable. Consequently, the read across target substance is consider readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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