Registration Dossier
Registration Dossier
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EC number: 224-030-0 | CAS number: 4170-30-3
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: full data not available, publication, non-glp
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 960
Materials and methods
- Type of study / information:
- irritant effects in humans
- Endpoint addressed:
- respiratory irritation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- humans exposed for 1 min through a mask connected to a hermetic chamber.
- GLP compliance:
- no
Test material
- Reference substance name:
- Crotonaldehyde
- EC Number:
- 224-030-0
- EC Name:
- Crotonaldehyde
- Cas Number:
- 4170-30-3
- Molecular formula:
- C4H6O
- IUPAC Name:
- but-2-enal
- Details on test material:
- none
Constituent 1
Method
- Details on study design:
- none
- Exposure assessment:
- not specified
Results and discussion
- Results:
- The threshold concentrations of crotonaldehyde vapor causing irritation at teh mucous membranes of the eyes and nose proved to be 0.0005-0.001 mg/L.
Any other information on results incl. tables
none
Applicant's summary and conclusion
- Conclusions:
- Threshold for irritation in humans for 1 min is very very low and not analytically verified.
- Executive summary:
none
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
