Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data is from authoritative database
Justification for type of information:
Data is from authoritative database
Reference:
Composition 1
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Water solubility of 5-acetamido-2-aminobenzenesulphonic acid was determined.
GLP compliance:
not specified
Type of method:
other: no data
Test material information:
Composition 1
Specific details on test material used for the study:
- Name of test material: 5-acetamido-2-aminobenzenesulphonic acid
- IUPAC name: 2-amino-5-acetamidobenzene-1-sulfonic acid
- Molecular formula: C8H10N2O4S
- Molecular weight: 230.243 g/mole
- Smiles :O=C(Nc1ccc(N)c(S(=O)(=O)O)c1)C
- Inchl: 1S/C8H10N2O4S/c1-5(11)10-6-2-3-7(9)8(4-6)15(12,13)14/h2-4H,9H2,1H3,(H,10,11)(H,12,13,14)
- Substance type: Organic
- Physical state: Solid crystal powder (white to yellowish grey)
Key result
Water solubility:
13 500 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
Remarks on result:
other: no other details available
Conclusions:
The water solubility of 5-acetamido-2-aminobenzenesulphonic acid was determined to be 13500 mg/L at 20 °C.
Executive summary:

Based on available data from authoritative database, the water solubility of chemical 5-acetamido-2-aminobenzenesulphonic acid was determined to be 13500 mg/L at 20 °C.

Based on the determined value, the substance 5 -acetamido-2-aminobenzenesulphonic acid was considered to be very soluble in water.

Description of key information

The water solubility of 5-acetamido-2-aminobenzenesulphonic acid was determined to be 13500 mg/L at 20 °C.

Key value for chemical safety assessment

Water solubility:
13 500 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of 5-acetamido-2-aminobenzenesulphonic acid from two different studies summarized below,

First study based on available data from authoritative database, determined the water solubility of chemical 5-acetamido-2-aminobenzenesulphonic acid as 13500 mg/L at 20 °C.

Other supporing studies from EPI suite, estimated water solubility of the substance 5-acetamido-2-aminobenzenesulphonic acid by using WSKOW v1.42. The estimated water solubility of the substance 5-acetamido-2-aminobenzenesulphonic acid was considered to be 5163 mg/l at 25 deg C.

Based on these values, the substance 5 -acetamido-2-aminobenzenesulphonic acid was considered to be very soluble to soluble in water.