(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

September 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted according to OECD 104 and EU A.4 guidelines, under GLP without deviation and with certificate of analysis included.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Key result

Temp.:

20 °C

Vapour pressure:

ca. 0.017 Pa

The measured values for temperature and vapour pressure are evaluated as follows: a graph with log p vs 1/T is plotted. Since these values are correlated by a linear relation, the data can be fitted to a linear graph. Slope and intercept of the regression as well as the regression coefficient r are stated.

Parameters of linear regression

Parameter	Value
Slope	-6882.77
Intercept	21.71
Correlation Coefficient r	1.0000
Coefficient of Determination r^2	1.0000

 

Using the effusion method, two temperatures 30°C and 45°C were examined. The following vapour pressure were found:

1.03 *10-1 Pa at 30°C (standard deviation 9.11 * 10-3)

1.21 Pa at 45°C (standard deviation 6.47 * 10-2)

Using linear regression, the following vapour pressures for 20°C and 25°C were estimated:

1.71 * 10-2 Pa at 20°C

4.24 * 10-2 Pa at 25°C

The following vapour pressures were determined experimentally and considered as valid (mean and standard deviation given):

Experimentally Determined Vapour Pressures

T	T	P	Stand. Dev. P	RSD P
°C	K	Pa	Pa	%
30	303.2	1,03E-01	9,11E-03	8.9%
45	318.2	1.21E+00	6.47E-02	5.4%

Conclusions:

Using the effusion method according to OECD 104 guidelines and EU method A.4, the vapour pressure for the test item is 1.71.10-2 Pa at 20°C and 4.24.10-2 Pa at 25°C.

Executive summary:

Using the effusion method (weight loss) according to OECD 104 guidelines and EU method A.4, two temperatures 30°C and 45°C were examined.

The following vapour pressure were found:

1.03.10^-1 Pa at 30°C (standard deviation 9.11.10^-3)

1.21 Pa at 45°C (standard deviation 6.47.10^-2)

Using linear regression, the following vapour pressures for 20°C and 25°C were estimated:

1.71.10^-2 Pa at 20°C

4.24.10^-2 Pa at 25°C

Description of key information

 the effusion method (weight loss) according to OECD 104 guidelines and EU method A.4, two temperatures 30°C and 45°C were examined. 














  
  
  

The vapour pressure was determined using the effusion method according to OECD 104 and EU method A.4.










The vapour pressure of the test item at 20°C is 










The vapour pressure of the test item at 40°C is 














  
  
  



Using the effusion method according to OECD 104 guidelines and EU method A.4, the vapour pressure for the test item is:













































- 1.71.10-2 Pa at 20°C; 






















- and 4.24.10-2 Pa at 25°C.

















  
  






The following vapour pressure were found:
1.03 *10-1 Pa at 30°C (standard deviation 9.11 * 10-3)
1.21 Pa at 45°C (standard deviation 6.47 * 10-2)
Using linear regression, the following vapour pressures for 20°C and 25°C were estimated:
1.71 * 10-2 Pa at 20°C
4.24 * 10-2 Pa at 25°C

Key value for chemical safety assessment

Vapour pressure:

0.017 Pa

at the temperature of:

20 °C

Additional information

A key study was conducted according to OECD 104 and EU A.4 guidelines, under GLP without deviation and with certificate of analysis included. Therefore a reliability of 1 is assigned and the value obtained in this study is proposed as a key value.