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Toxicity to microorganisms

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Description of key information

A respiration inhibition test according to OECD Guideline 209 was performed with NPEO. The inhibition ranged from 5 to 29%. Due to the low inhibitions the EC20, EC50 and EC80 values of the test substance could not be calculated therefore the EC10 is expected to be > 100 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information

A test with NPEO was performed under static conditions at nominal concentrations 10, 32, 100, 320 and 1,000 mg/L. The respiration rates of control, reference and test substance concentrations were measured after a contact time of three h, and the inhibitory effects of the test and reference item were determined in comparison to the control respiration rates. The inhibition ranged from 5 % to 29 %. Due to the low inhibitions the EC20, EC50 and EC80 values of the test substance could not be calculated therefore the EC10 is expected to be > 100 mg/L (Fiebig S, 2010).