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Environmental fate & pathways

Biodegradation in water: screening tests

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Endpoint:
biodegradation in water: screening test, other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1984
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Qualifier:
no guideline available
Principles of method if other than guideline:
- Principle of test: Biochemical oxygen demand determined after 5 d at 20°C inoculation
- Parameters analysed / observed: oxygen content at 0 h and after 5 d inoculation
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial (adaptation not specified)
Duration of test (contact time):
5 d
Parameter:
% degradation (O2 consumption)
Remarks on result:
other: BOD5
Parameter:
BOD5
Value:
31 mg O2/g test mat.
Parameter:
COD
Value:
1 935 mg O2/g test mat.
Key result
Parameter:
BOD5*100/COD
Value:
2 mg O2/g test mat.
Validity criteria fulfilled:
not applicable
Interpretation of results:
not readily biodegradable
Conclusions:
The BSB5/COD ratio is 0.02. Therefore the substance is not considered to be readily biodegradable.
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to
Guideline:
OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
Version / remarks:
1981
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
- Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): ARA Birsfelden
Duration of test (contact time):
28 d
Initial conc.:
30 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
ThOD (test substance): 2.6 mg O2 / mg substance
Reference substance:
aniline
Key result
Parameter:
% degradation (O2 consumption)
Value:
0
St. dev.:
0
Sampling time:
26 d
Details on results:
The toxicity control did not indicate any inhibitory effect on activated sluge. The degradation rate was determined at 109% after 26 d based on O2 consumption.
Parameter:
BOD5
Value:
< 1 mg O2/g test mat.
Parameter:
COD
Value:
859 mg O2/g test mat.
Results with reference substance:
82% degradation after 26 d based on O2 consumption
Validity criteria fulfilled:
not specified
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
There was no biodegradation observed in an OECD 302C inherent biodegradabality test (0% after 26 d based on O2 consumption). The test substance is not considered to be inherently biodegradable.
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1979
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
No information given on negative control and validity criteria.
Qualifier:
according to
Guideline:
other: Modified OECD Confirmatory Tests
Version / remarks:
The test was conducted according to SOP A-12 (1974-09-01).
GLP compliance:
no
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial (adaptation not specified)
Duration of test (contact time):
39 d
Initial conc.:
20 mg/L
Based on:
TOC
Initial conc.:
59.7 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
TOC removal
Details on study design:
TEST CONDITIONS
- Composition of medium: TOC content of medium: 118 mg/L

TEST SYSTEM
- Number of culture flasks/concentration: 1


CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
Key result
Parameter:
% degradation (TOC removal)
Value:
91
St. dev.:
6
Sampling time:
21 d
Parameter:
BOD5
Value:
150 mg O2/g test mat.
Remarks on result:
other: Test item conc. 20 mg/L
Parameter:
COD
Value:
1 008 mg O2/g test mat.
Remarks on result:
other: Test item conc. 10 mg/L
Validity criteria fulfilled:
not specified
Interpretation of results:
inherently biodegradable
Conclusions:
The substance was found to be inherently biodegradable (91% after 21 d based on TOC removal).

Description of key information

Based on a weight-of-evidence approach with several BOD/COD measurements, a Confirmatory OECD 2 test (inherent biodegradability) and an OECD 302C MITI II (inherent biodegradability) which is the most reliable source, the substance is considered to be neither inherently nor readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information