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EC number: 219-307-8 | CAS number: 2408-20-0
Endpoint summary
Administrative data
Description of key information
Biodegradation in water:
Biodegradability of test chemical 2-Propenyl Propanoate (CAS No.2408-20-0) was predicted using OECD QSAR tool box v.3.3 using log Kow as primary descriptor.Percent Biodegradation of test chemical 2-Propenyl Propanoate estimated was 87.80 % by using BOD parameter and microorganisms as inoculum in 28 days. By this value of percent biodegradation it is concluded that test chemical 2-Propenyl Propanoate is readily biodegradable.
Biodegradation in water and sediments :
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound2-Propenyl Propanoate(CAS No. 2408 -20 -0). If released in to the environment, 40.2 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical 2-Propenyl Propanoate in sediment is estimated to be135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.106 %), indicates that test chemical 2-Propenyl Propanoate is not persistent in sediment.
Biodegradation in soil:
The half-life period of test chemical 2-Propenyl Propanoate (CAS No.2408-20-0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 57.4% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical 2-Propenyl Propanoate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical 2-Propenyl Propanoate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .
Additional information
Biodegradation in water:
Predicted data for target compound 2-Propenyl Propanoate (CAS No.2408-20-0) and supporting weight of evidence studies for its closest read across chemicals with log Kow as a primary descriptor were reviewed for the biodegradation endpoint which is summarized below.
Biodegradability of test chemical 2-Propenyl Propanoate (CAS No.2408-20-0) was predicted using OECD QSAR tool box v.3.3 using log Kow as primary descriptor. Percent Biodegradation of test chemical 2-Propenyl Propanoate estimated was 87.80 % by using BOD parameter and microorganisms as inoculum in 28 days. By this value of percent biodegradation it is concluded that test chemical 2-Propenyl Propanoate is readily biodegradable.
Another prediction done by using Estimation Programs Interface Suite (EPI suite, 2017) to estimate the biodegradation potential of the test compound 2-Propenyl Propanoate (CAS no. 2408-20-0) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical 2-Propenyl Propanoate is expected to be readily biodegradable.
In a supporting weight of evidence study done from authoritative database (J Check, 2017) biodegradation experiment was carried out of read across chemical ethenyl propanoate (CAS no. 105-38-4) by taking activated sludge as inoculums at 30 mg/L concentration for 28 days. Biodegradation was analyzed by using two parameters namely BOD and GC. The initial concentration of read across chemical was100 mg/L after 28 days of incubation percent biodegradation of test chemical ethenyl propanoate was observed to be 93 % by BOD parameter 100 % by GC parameter. Therefore it is concluded that test chemical ethenyl propanoate is readily biodegradable.
Another supporting weight of evidence study done from same source as mentioned above (J Check) for read across chemical Diethyl Ethanedioate (CAS no. 95-92-1).The read across chemical Diethyl Ethanedioate was subjected to biodegradation test by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analyzed by using three parameters that are BOD, TOC and HPLC. The initial concentration of read across chemical was 100 mg/L and study design was of standard type. After 28 days of incubation the read across chemical Diethyl Ethanedioate undergoes 80 % degradation by considering BOD parameter, 100 % degradation by taking other two parameters that are TOC and HPLC. Thus based on percent biodegradability it is concluded that read across chemical Diethyl Ethanedioate is readily biodegradable.
On the basis of above results for target chemical 2-Propenyl Propanoate (CAS no. 2408-20-0) (from OECD QSAR tool box and EPI suite, 2017) and for its read across substance (from authoritative database), it is concluded that the test substance2-Propenyl Propanoate is expected to be readily biodegradable in nature.
Biodegradation in water and sediments :
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound2-Propenyl Propanoate (CAS No. 2408 -20 -0). If released in to the environment, 40.2 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical 2-Propenyl Propanoate in sediment is estimated to be135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.106 %), indicates that test chemical 2-Propenyl Propanoate is not persistent in sediment.
Biodegradation in soil:
The half-life period of test chemical 2-Propenyl Propanoate (CAS No.2408-20-0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 57.4% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical 2-Propenyl Propanoate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical 2-Propenyl Propanoate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .
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