Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1989-06-19
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Abstract

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: DIN 38412, part 15
Deviations:
not specified
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4(or 2,4,4)-trimethyladipic acid
EC Number:
258-556-7
EC Name:
2,2,4(or 2,4,4)-trimethyladipic acid
Cas Number:
53445-37-7
Molecular formula:
C9H16O4
IUPAC Name:
2,2,4-trimethylhexanedioic acid; 2,4,4-trimethylhexanedioic acid
Details on test material:
(2,2,4/2,4,4)-Trimethyladipic acid of Hüls AG, purity not reported

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Leuciscus idus
Details on test organisms:
TEST ORGANISMS
- Strain: Leuciscus idus melanotus
- Wild caught: no

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Details on test conditions:
TEST SYSTEM
- Renewal of test solution: no
- Exposure vessel type: 10 l solution in 18 l aquarium
- Number of replicates, fish per replicate: 1, 10 - Adjustment of pH: no
TEST PARAMETER: mortality
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
400 mg/L
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
502 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The 48 h-LC50 of 2,2,4(or 2,4,4)-trimethylhexanedioic acid for Leuciscus idus melanotus was determined as 502 mg/l according to the German Standard DIN 38412, part 15.
Executive summary:

The 48 h-LC50 of 2,2,4(or 2,4,4)-trimethylhexanedioic acid for Leuciscus idus melanotus was determined as 502 mg/l according to the German Standard DIN 38412, part 15.