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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Biodegradation in water:

Biodegrdability of test chemical Tetraoctylammonium Bromide ( CAS no. 14866 -33 -2) is predicted using OECD QSAR tool box v.3.4 using log Kow as primary descriptor. The test chemical Tetraoctylammonium Bromide undergoes 0.060 % percent biodegrdadation by taking BOD as parameter and by taking microorganisms as inoculum in 28 days. So it is concluded that the test chemical Tetraoctylammonium Bromide is not readily biodegradable.

Biodegradation in water and sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Tetraoctylammonium Bromide (CAS No.14866-33-2). If released in to the environment, 4.85 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical Tetraoctylammonium Bromide in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical Tetraoctylammonium Bromide in sediment is estimated to be 135 days (3240  hrs). Based on this half-life value, it indicates that test chemical Tetraoctylammonium Bromide is persistent in sediment.

Biodegradation in Soil:

The half-life period of test chemical Tetraoctylammonium Bromide (CAS No. 14866-33-2) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 32.7 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical Tetraoctylammonium Bromide in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical Tetraoctylammonium Bromide, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.

Additional information

Biodegradation in water:

Results of predicted data for target compound Tetraoctylammonium Bromide (CAS no. 14866-33-2) and supporting weight of evidence studies for its read across chemicals were reviewed for the biodegradation endpoint which is summarized below.

Biodegrdability of test chemical Tetraoctylammonium Bromide (CAS no. 14866-33-2) is predicted using OECD QSAR tool box v.3.4 using log Kow as primary descriptor. The test chemical tetraoctylammonium Bromide undergoes 0.060 % percent biodegrdadation by taking BOD as parameter and by taking microorganisms as inoculum in 28 days. So it is concluded that the test chemical Tetraoctylammonium Bromide is not readily biodegradable.

Another prediction done by using Estimation Programs Interface Suite (EPI suite, 2017) to estimate the biodegradation potential of the test compound Tetraoctylammonium Bromide (CAS no.14866-33-2) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Tetraoctylammonium Bromide is expected to be not readily biodegradable.

In a supporting weight of evidence study done from authoritative database (J Check, 2017) the Biodegradation experiment was carried out of read across chemical N,N-dioctyl-1-octanamine (CAS no. 1116-76-3) by taking activated sludge as inoculums at 100 mg/L concentration for 14 days. Biodegradation was analyzed by using two parameters that are BOD and test material analysis by GC. The initial concentration of read across chemical was 30 mg/L. After 2 weeks of incubation percent biodegradation of read across chemical N,N-dioctyl-1-octanamine was observed 0.0 % by BOD parameter 12 % by test material analysis by GC parameter in 14 days. Therefore it is concluded that read across chemical N,N-dioctyl-1-octanamine is not readily biodegradable.

Another supporting weight of evidence study done from same source as mentioned above (J Check, 2017) for read across chemical Didecyl dimethyl ammonium chloride (CAS no. 7173-51-5). Biodegradation study was conducted for 28 days for evaluating the percent biodegradability of read across substance Didecyl dimethyl ammonium chloride. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)).Concentration of inoculum i.e., sludge used was 30 mg/l and initial read across substance conc. used in the study was 100 mg/l. The percentage degradation of read across substance was determined to be 0% degradation byO2 consumption (BOD) and Test material analysis by LC-MS in 28 days. Thus, based on percentage degradation, Didecyl dimethyl ammonium chloride was considered to be not readily biodegradable in nature.

 

On the basis of above results for target chemicalTetraoctylammonium Bromide (CAS no.14866-33-2)(from OECD QSAR tool box and EPI suite, 2017) and for its read across substance (from authoritative database), it is concluded that the test substance Tetraoctylammonium Bromide is expected to be not readily biodegradable in nature.

Biodegradation in water and sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Tetraoctylammonium Bromide (CAS No.14866-33-2). If released in to the environment, 4.85 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical Tetraoctylammonium Bromide in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical Tetraoctylammonium Bromide in sediment is estimated to be 135 days (3240  hrs). Based on this half-life value, it indicates that test chemical Tetraoctylammonium Bromide is persistent in sediment.

Biodegradation in Soil:

The half-life period of test chemical Tetraoctylammonium Bromide (CAS No. 14866-33-2) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 32.7 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical Tetraoctylammonium Bromide in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical Tetraoctylammonium Bromide, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.