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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Calcination products of titanium dioxide, tin monoxide, zinc oxide and dihydrogen wolframate
EC Number:
941-788-4
Molecular formula:
Ti 1 Sn 0,6 Zn 0,5 W 0,15 O 4
IUPAC Name:
Calcination products of titanium dioxide, tin monoxide, zinc oxide and dihydrogen wolframate
Details on test material:
- Physical state: solid, red
- Analytical purity: > 99 %
- Storage condition of test material: room temperature

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
Analysis of the test media samples for Sn was conducted on fresh media at 0 hours and on
corresponding old media at 96 hours. Measured test concentrations were determined
from samples of control and test solution.

Test solutions

Vehicle:
no
Details on test solutions:
Due to the fact that the test substance is inorganic with a very low water solubility a WAF was prepared. The test substance was added into 6 L test water and stirred for 24 hours. Then, undissolved test substance was allowed to settle for about one hour. Dispersion was taken from the middle of the vessel and filtered at 0.45 µm.

Test organisms

Test organisms (species):
other: Chinese Rare Minnow (Gobiocypris rarus)
Details on test organisms:
Fish were bred in the lab.
Fish were acclimatized to the test conditions for more than 14 days prior the test.

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Test conditions

Hardness:
Total hardness as CaCO3 (mg/L): 125
Test temperature:
21.9-22.3 °C
pH:
7.33-7.72
Dissolved oxygen:
78-93%
Nominal and measured concentrations:
measured concentrations remained
within ± 20 % Sn of the start concentration (geometric mean of 5.12 µg Sn/L)

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EL50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat. (total fraction)
Basis for effect:
mortality (fish)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes

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