Registration Dossier
Registration Dossier
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Reaction products of 1-(substitutedphenyl)urea coupled with diazotated potassium sodium substituted-5-{[2-(substituted)ethyl]sulfonyl}benzenesulfonate, further condensed with 2,4,6-trichloro-1,3,5-triazine, further converted with disubstituted benzene-1,4-disulfonic acid in aq. sodium hydroxide
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Aquatic acute tests covering 3 trophic levels, (algae, fish and invertebrate), were conducted. Activated sludge respiration inhibition data is also presented.
In accordance with column 2 of REACH Annex VIII-X, the acute Daphnia study does not need to be conducted if a long-term aquatic toxicity study on invertebrates is available (performed for China Level II notification; according to Guidance for New Chemical Substance Notification" (September, 2010)).
All the aquatic studies were conducted in accordance with GLP and OECD guidance and endpoints were based on nominal concentrations.
- In an OECD 203 acute fish toxicity test the 96 hour LC50 was found to be greater than 100 mg/L.
- The OECD 202 acute Daphnia magna test was not performed as a long-term aquatic toxicity study on invertebrates is available (performed for China Level II notification; according to Guidance for New Chemical Substance Notification" (September, 2010)).
- In an OECD 211 Long-term toxicity to aquatic invertebrates, the 21-Day EC50 (immobilization) value, based on nominal test concentrations, for the parental daphnia generation (P1) was calculated to be 84 mg/L.
The 21-Day EC50 (reproduction) based on nominal test concentrations was 94 mg/L with 95% confidence limits of 76 to 96 mg/L.
The "Lowest Observed Effect Concentration" (LOEC) and the "No Observed Effect Concentration" (NOEC) for reproduction based on nominal test concentrations were 100 and 56 mg/L respectively.
The "Maximum Acceptable Toxicant Concentration" (MATC) was calculated to be 75 mg/L.
- In an OECD 201 algal inhibition test the 72 hour ErC50 for growth rate was found to be greater than 100 mg/L and the NOEC was found to be 100 mg/L.
- In an OECD 209 activated sludge respiration inhibition test, the 3 hour EC50 was determined to be greater than 1000 mg/L
In conclusion there is no indication of toxicity of FAT40871/A TE to the aquatic environment.
Additional information
Based on the results, FAT 40871 is not classified for the aquatic environment according to CLP (regulation 1272/2008) criteria.
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