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The hydrolysis properties of the test item, FAT 40871/A TE, were tested in a valid GLP study in accordance with the OECD Guideline 111 (Hydrolysis as a Function of pH).

The substance was found to be hydrolytically stable at pH 4, 7 and 9 with a predicted half-life of 1 year, 99.4 hours and 182 days respectivelly at 25 °C.

As the pH 7 and pH 9 results indicate that the rate of hydrolysis increases with a decrease in pH, it can be concluded that the test item will hydrolyse extremely rapidly at pH 4. However, as this wasn’t indicated by the pH 4 results, it is likely that the main “test item” peak in the pH 4 standards and samples was due to a stable, hydrolysis product (as opposed to the parent test item).