Registration Dossier
Registration Dossier
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EC number: 609-080-7 | CAS number: 35160-38-4
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to daphnia
In one key study with Daphnia magna (OECD 202) no effects were observed at nominal concentrations of the test item phoshinic acid, diethyl-, sodium salt up to 1100 mg/L (NOEC 1100 mg/L).
This is supported by three acute immobilization tests with Daphnia magna according to OECD Guideline 202.
Two studies performed with the read across substance phosphinic acid, diethyl, aluminium salt result in 48 h-EC50 values > 100 mg/L based on the nominal test item concentration. The NOEC after 48 h was 100 mg/L.
The third test was performed with the read across substance diethyl, phosphinic acid. Based on the nominal concentrations of the test item the 48-h EC50 for Daphnia magna was estimated to be 70.7 mg/L. The NOEC after 48 h was 50.0 mg/L. The LOEC after 48 h was 100 mg/L.
The effects observed at the concentration level of 100 mg/L were caused by the low pH-values (pH below the recommended range of pH 6 – 9). This was confirmed by the pH-neutralized concentration level of 100 mg/L which caused no effects on Daphnia magna. Based on the pH-neutralized concentration the 48-h EC50 and the NOEC for Daphnia magna were > 100 mg/L.
Toxicity to algae
There are two tests with freshwater green alga Desmodesmus subspicatus available. The effects of the test item were determined according to OECD Guideline 201.
One studie performed with the read across substance phosphinic acid, diethyl, aluminium salt result in 72 h-EC50 values > 180 mg/L based on the nominal test item concentration. The NOEC after 72 h was 180 mg/L.
The second test was performed with the read across substance diethyl, phosphinic acid.In this study the test item was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 hours with the following effect values (geometric mean measured test item concentrations). The NOEC-values for inhibition of growth rate and inhibition of yield after 72 hours were 52.3 mg/L and 14.6 mg/L, respectively. The EC50-values for inhibition of growth rate (ErC50) and yield (EyC50) with 95 % confidence intervals after 72 hours were 60.9 and 59.5 mg/L, respectively.
The effects were caused by the low pH-values. This was confirmed by the pH-neutralized concentration level of 98.9 mg/L (geometric mean measured) which caused no effects on the algae growth. Based on the pH-neutralized concentration the NOEC-values for both the inhibition of the growth rate and the inhibition of the yield after 72 hours were 98.9 mg/L. The EC50-values for both inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were > 98.9 mg/L. All effect levels are given based on geometric mean measured concentrations of the test item.
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