Registration Dossier
Registration Dossier
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EC number: 807-008-0 | CAS number: 1173693-36-1
Endpoint summary
Administrative data
Description of key information
Not a dermal sensitizer
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A Magnusson-Kligman maximization test (OECD 406) was conducted with guinea pigs to determine the potential for the test substance to invoke dermal skin sensitisation reactions. At the 48 hour challenge reading the irritation score for the test group animals and test vehicle control/naive animals was 0 for 29 of 30 animals. One test group animal at the 65% dose had a reading of 0.5. A reading of 0.5 - very faint erythema is not considered a positive reaction. Based on the results of this study, the test substance is considered not to be a contact skin sensitiser.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
There was no evidence of dermal sensitisation in guinea pigs. The substance does not need to be classified for skin sensitisation according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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