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EC number: 294-705-2 | CAS number: 91745-35-6
An acute dermal toxcity study (limit test) was conducted in Sprague-Dawley CD rats using a dose of 2,000 mg of test material (moistened with arachis oil BP) per kg bodyweight, applied under semi-occlusive dressing for 24 hours and followed by a 14 -day observation period. This GLP study was conducted in accordance with OECD Test Guideline 402, except that, following removal of the test material, animals were group-housed (by sex), but this is not considered to have affected study reliability.
No animals died during the study and no signs of toxicity or adverse effects were observed in-life or at necropsy. The LD50 of the test material in Sprague-Dawley rats is concluded to be >2,000 mg/kg bodyweight.
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