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Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
9 December 2016 - 20 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. QA statement)
Remarks:
dated 14 January 2016
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
mass spectrometry
Key result
Type:
log Pow
Partition coefficient:
-0.1
Temp.:
20 °C
pH:
6.5
Details on results:
Average = - 0.1 (+/- 0.2)
We can then consider that there is no partition for this test item.

The results of Log (Pow) agree well with OECD 107 requirement (less than 0.3 units deviation between lowest and highest values of Log (Pow)).
Conclusions:
Log (Pow) = - 0.01 ± 0.2 at 20°C and pH = 6.5.
We can then consider that there is no partition for this test item.

Description of key information

Under the experimental conditions of the test carried out according to OECD 107 guideline, log (Pow) of test item was estimated to be -0.1 (+/- 0.2) at 20°C and pH = 6.5.

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.1
at the temperature of:
20 °C

Additional information

We can then consider that there is no partition for this test item