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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29 Nov 1999 - 3 Dec 1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: done under OECD method and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EC Directive 92/69/EEC, Part C, Method C1
GLP compliance:
yes

Test material

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Direct addition of test substance to diluent water, with ultrasonication to aid dispersion.

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
static

Test conditions

Hardness:
134 - 155 mg/l

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
19.2 mg/L
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
19.2 mg/L
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
10.2 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
8.4 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
18.7 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
1.9 mg/L

Applicant's summary and conclusion

Conclusions:
The 96 hour LC50 value with rainbow trout was 8.4mg/l
The "no-observed effect concentration" (NOEC) with rainbow trout was 1.9mg/l
Executive summary:

In a 96h static acute toxicity to fish test on Oncorrhynchus mykiss (rainbow trout), the LC50 value for the test substance BMS 217947 -01, was 8.4 mg/l. The NOEC was 1.9 mg/l.