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EC number: 701-124-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biological effects monitoring
Administrative data
- Endpoint:
- biological effects monitoring
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Very complete and well documented study that gives proper information on the potential consequences of an accidental spill in standing waters.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test material
- Reference substance name:
- 9016-87-9
- Cas Number:
- 9016-87-9
- IUPAC Name:
- 9016-87-9
- Reference substance name:
- Isocyanic acid, polymethylenepolyphenylene ester
- IUPAC Name:
- Isocyanic acid, polymethylenepolyphenylene ester
- Details on test material:
- Polymeric MDI, 46.8% monomer. (Desmodur 44V20; Bayer AG).
Constituent 1
Constituent 2
Results and discussion
Any other information on results incl. tables
The hydrolytic degradation of the MDI layer to insoluble polymerised product (virtually 100%), with some evolution of CO2 in the early stages, was observed. Neither MDI nor MDA (diaminodiphenylmethane, an intermediate in the hydrolysis - cf section 5.1.2) was detectable in the pond water at any stage (<0.005 mg/l), or was accumulated in the fish (detection limits 0.36 mg/kg and 0.69 mg/kg respectively). The pH of the treated ponds fell during the study, by ca 2.0 and 0.7 units for the high and low dosed ponds respectively, this due to liberation of CO2 which also caused an increase in hardness. The biological and chemical oxygen demand were not affected by either application rate of MDI. Neither dose rate caused any direct effect on the pelagic community (phytoplankton, zooplankton, fish, macrophytes) of the test ponds. Some minor indirect effects caused by the production of CO2 were observed in phyto- and zoo- plankton community structures and an increase in macrophyte growth was noted (42% higher than control for the high dose pond). Organisms living in sediment (macrobenthos) were affected by physical obstructions in the habitat (e.g. the crust of hydrolysing MDI) but regained densities equivalent to control after some weeks except for Bivalvia which have too long a generation time for the test period. Satisfactory homogeneous analysis of the sediment was rendered difficult because test substance had spilt over onto the untreated sediment layer.(This layer was actually covered by test substance in the high dose pond). In consequence, relatively high concentrations of MDI were detected in the high-dose pond sediment during the early stages of the test (widely varying, up to 14.5 g/kg) but these declined throughout the study, to ca 0.5 mg/kg. In the low-dose pond a mean concentration in sediment of 5 mg/kg on day 7 declined to <= 0.5 mg/kg at the end of the test. MDA was not detected in the sediment except on day 7, when 12 mg/kg for the high-dose pond and 7 mg/kg (one reading only) for the low-dose pond were detected. (The detection limit was 0.3 mg/kg.)
Applicant's summary and conclusion
- Executive summary:
The hydrolytic degradation of the MDI layer to insoluble polymerised product (virtually 100%), with some evolution of CO2 in the early stages, was observed. Neither MDI nor MDA (diaminodiphenylmethane, an intermediate in the hydrolysis - cf section 5.1.2) was detectable in the pond water at any stage (<0.005 mg/l), or was accumulated in the fish (detection limits 0.36 mg/kg and 0.69 mg/kg respectively). The pH of the treated ponds fell during the study, by ca 2.0 and 0.7 units for the high and low dosed ponds respectively, this due to liberation of CO2 which also caused an increase in hardness. The biological and chemical oxygen demand were not affected by either application rate of MDI. Neither dose rate caused any direct effect on the pelagic community (phytoplankton, zooplankton, fish, macrophytes) of the test ponds. Some minor indirect effects caused by the production of CO2 were observed in phyto- and zoo- plankton community structures and an increase in macrophyte growth was noted (42% higher than control for the high dose pond). Organisms living in sediment (macrobenthos) were affected by physical obstructions in the habitat (e.g. the crust of hydrolysing MDI) but regained densities equivalent to control after some weeks except for Bivalvia which have too long a generation time for the test period. Satisfactory homogeneous analysis of the sediment was rendered difficult because test substance had spilt over onto the untreated sediment layer.(This layer was actually covered by test substance in the high dose pond). In consequence, relatively high concentrations of MDI were detected in the high-dose pond sediment during the early stages of the test (widely varying, up to 14.5 g/kg) but these declined throughout the study, to ca 0.5 mg/kg. In the low-dose pond a mean concentration in sediment of 5 mg/kg on day 7 declined to <= 0.5 mg/kg at the end of the test. MDA was not detected in the sediment except on day 7, when 12 mg/kg for the high-dose pond and 7 mg/kg (one reading only) for the low-dose pond were detected. (The detection limit was 0.3 mg/kg.)
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