Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
according to guideline
OECD Guideline 112 (Dissociation Constants in Water)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Test material form:
solid: particulate/powder
migrated information: powder
Details on test material:
Name of test material (as cited in study report): (1 , 1'-Biphenyl) -2-amine,3',4', 5'-trifluoro-
Physical state: solid
Analytical purity: 100.0 % (1H-NMR, see characterization study no. 15L00258)
BASF SE, D-67056 Ludwigshafen
Lot/batch No.: SK03/186
Expiration date of the lot/batch:Mar 22, 2015
Storage condition of test material:Room temperature, protection against humidity

Results and discussion

Dissociating properties:

Any other information on results incl. tables

The water solubility of the test item is 50 mg/L (see study no. 15L00260).

Probably due to this low water solubility no reproducible titration er clear evaluation of the titration data was possible.

The determination cf the dissociation constant of an aqueous preparation of the test item was not possible.

Applicant's summary and conclusion