Registration Dossier
Registration Dossier
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EC number: 943-670-8 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) > 100 mg/l equivalent to 80.3 mg/l of active ingredient.
EC5 (48 h) = 100 mg/l equivalent to 80.3 mg/l of active ingredient
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Due to the lack of details in the available study on Disperse Blue 073, a read across approach was used in order to complete the assessment for toxicity to aquatic algae. A detailed description of the read across chosen is reported in section 13.
One test is available on similar substance 1 (Huntsman, 1997), where acute toxicity of the test substance to Daphnia magna was determined according to OECD guideline 202 "Daphnia sp., Acute Immobilization Test." The test gave EC50 (48 h) > 80.3 mg/l, in terms of active ingredient. In particular, 80.3 mg/l corresponds to EC5.
Water solubility of the tested substance is << 0.02 g/l as determined by the flask method in OECD guideline 105. This implies that, at concentrations tested, an amount of test substance is undissolved (1) (2). However, available data in the test indicates that no immobilization is seen at concentration of 45 mg/l and 5 % immobilization (1/20 organisms) at 100 mg/l, but no data is available whether such immobilization is caused by inherent toxicity or physical effects of undissolved substance.
Therefore, on these bases, it can be concluded that the substance is non-toxic to Daphnia magna at the concentrations tested in excess of water solubility.
(1) ANALYSIS REPORT N. RC / 025-2 / 15, ARS TINCTORIA, 2015
(2) ETAD Project E 3020 Ecological Assessment of Important Dyestuffs, DyStar Colours Distribution GmbH, 1990
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