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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26-Jan to 29-Jan 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Remarks:
Staatliches Gewerbeaufsichtsamt Hildeshelm
Type of method:
column elution method
Key result
Water solubility:
2.41 mg/L
Temp.:
20 °C
pH:
7

Results

 

Solubility Results for test item at 20 °C (dilution factor of 2 and exact weight of the external standards taken into account; mean values of two injections)

 

Sample

Test item [mg/L]

 

 

at 0.4 mL/min

at 0.2 mL/min

 

1

2.58

2.20

 

2

2.68

2.11

 

3

2.61

2.24

 

4

2.62

2.18

 

5

2.64

2.20

Overall [mg/L]

Mean

2.63

2.19

2.41

Deviation (%)

41)

61)

202)

SD +/-

0.17

0.09

 

 

Conclusions

The solubility of the test item in double distilled water was determined to be 2.41 mg/L (pH 7) at 20 ± 0.5 °C.

Conclusions:
A water solubility value of 2.41 mg/L (at 20 °C, pH 7) was determined for the test substance according to E.U. Method A.6.

Description of key information

Water solubility: 2.41 mg/L at 20 °C, pH 7 (EU Method A.6., column elution method)

Key value for chemical safety assessment

Water solubility:
2.41 mg/L
at the temperature of:
20 °C

Additional information