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EC number: 264-780-6 | CAS number: 64338-16-5
Hydrolysis Results for the test item at pH 4 and 50 °C
Hydrolysis Results for the test item at pH 7 and 50 °C
Hydrolysis Results for the test item at pH 9 and 50 °C
Hydrolysis as a function of pH was determined according to OECD Guideline No. 111 and Council Regulation (EC) No. 440/2008, Method C.7 for the test item.
The study was conducted with test item concentrations of 1.5 mg/L in buffer solutions at pH 4, 7 and 9 at a test temperature of 50 °C (preliminary test).
Samples were taken at test start (0 hours) and test end (120 hours) and analysed via LC-MS on a reversed phase column using an external standard. Buffer solutions were analysed at test start and test end and indicated no interference with the test item. The analytical method for determination of the test item was validated and tested with satisfactory results in regard to linearity, accuracy, precision and specificity.
Degradation was calculated as the percentage loss of the test item over the time. In the preliminary test, the test item was found to be stable at pH 4, 7 and 9, respectively. No further testing was deemed necessary as less than 10 % of the applied test item were transformed after 120 hours (5 days) at each of the three pH values (Table 1). Reaction rate constants and half lives could not be calculated because the test item undergoes no significant hydrolysis. With respect to the guidelines a half life of > 1 year could be assumed for ambient temperature conditions.
Degradation [%] of the test item at 50 °C after 120 Hours
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