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Environmental fate & pathways

Endpoint summary

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Description of key information

Biodegradation in water:

Biodegradability of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is predicted using OECD QSAR tool box v.3.3 using log Kow as primary descriptor. The test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate undergoes 16 % biodegradation by taking BOD as parameter and microorganisms as inoculum in 28 days. Therefore it is concluded that test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is not readily biodegradable.

Biodegradation in water and Sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS No. 102-22-7). If released in to the environment, 10.5 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 37.5 days (900 hrs). The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate in sediment is estimated to be 337.5 days (3240 hrs). Based on this half-life value, it indicates that test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is persistent in sediment.

Biodegradation in soil:

The half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS No.102-22-7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 78.3 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .

Additional information

Biodegradation in water:

Predicted data for target compound (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS no. 102-22-7) and supporting weight of evidence studies for its closest read across chemicals with log Kow as a primary descriptor were reviewed for the biodegradation endpoint which are summarized as below.

Biodegradability of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS no.102-22-7) is predicted using OECD QSAR tool box v.3.3 using log Kow as primary descriptor. The test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate undergoes 16 % biodegradation by taking BOD as parameter and microorganisms as inoculums in 28 days. Therefore it is concluded that test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is not readily biodegradable.

Another prediction done by using Estimation Programs Interface Suite (EPI suite, 2017) to estimate the biodegradation potential of the test compound (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS no.102-22-7) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is expected to be not readily biodegradable.

In a supporting weight of evidence study from authoritative database ( J Check, 2017) the Biodegradation experiment was carried out for read across chemical eth(5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate (CAS no.10453-86-8) by taking activated sludge as inoculums at 30 mg/L concentration for 28 days. Biodegradation was analyzed by using two parameters namely BOD and HPLC. The initial concentration of read across chemical was 100 mg/L. After 28 days of incubation percent biodegradation of read across chemical eth(5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate was observed to be 0.0 % by BOD parameter 1.0 % by HPLC parameter.Therefore it is concluded that read across chemical eth(5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate is not readily biodegradable.

In another supporting weight of evidence study from same source as mentioned above (J check, 2017) of read across chemical 1,1'-[oxybis(methylene)]dibenzene (CAS no.103-50-4) biodegradation experiment was carried out by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analyzed by using two parameters that are BOD and HPLC. The initial concentration of read across chemical was 100 mg/L and study design was of standard type. After 14 days of incubation the read across chemical 1,1'-[oxybis(methylene)]dibenzene undergoes 0.0 % degradation by considering BOD as parameter and 7.0 % degradation by considering HPLC as parameter. Thus based on percent biodegradability it is concluded that read across chemical 1,1'-[oxybis(methylene)]dibenzene is not readily biodegradable.

On the basis of above results for target chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS no.102-22-7) from ( EPI suite 2017 and OECD QSAR tool box v3.3 2017) and for its read across substances (from J Check,2017) the target chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate expected to be not readily biodegradable.

Biodegradation in water and Sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS No.102-22-7). If released in to the environment, 10.5 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 37.5 days (900 hrs). The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate in sediment is estimated to be 337.5 days (3240 hrs). Based on this half-life value, it indicates that test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate is persistent in sediment.

Biodegradation in soil:

The half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate (CAS No.102-22-7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 78.3 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of test chemical (2E)-3,7-dimethylocta-2,6-dien-1-yl 2-phenylacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low .