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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution

Test material

Constituent 1
Reference substance name:
Rye, ext.
EC Number:
290-271-3
EC Name:
Rye, ext.
Cas Number:
90106-48-2
IUPAC Name:
Oligosaccharides and polysaccharides of glucose from Rye
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: white powder
- Storage In darkness at room temperature
- Batch: 16 167
- Manufacturing date: June 2016
- Expiry date: June 2018
Specific details on test material used for the study:
Particle size: non spherical
Particle size refractive index: 1.538 (sugars)
Particle size absorption index: 0.010 (sugars)
Approximate density of the powder: 1 g/cm3

Results and discussion

Particle sizeopen allclose all
Key result
Percentile:
D50
Mean:
ca. 85.1 µm
St. dev.:
0.33
Key result
Percentile:
D10
Mean:
ca. 44 µm
St. dev.:
2.86
Key result
Percentile:
D90
Mean:
ca. 152 µm
St. dev.:
0.71

Any other information on results incl. tables

9 measurements were made during the passage of the powder in the apparatus, the particle size distribution of COHELISS®AT is a Gaussian distribution between 11 µm and 120 µm with a peak at 89.4 µm and additionally a small fraction of fine particle down to 6 µm.

D50was averaged on the 9 measures with a Relative Standard Deviation (RSD) of 0.28%: D50= 85.1 µm.

As the relative standard deviation is below 3%, the measurement is considered to comply with the International Standard.

The additional following data were determined:

·        D10= 44 µm (the diameter at which 10% of the sample's mass is comprised of particles with a diameter less than this value)

·        D90= 152 (the diameter at which 90% of the sample's mass is comprised of particles with a diameter less than this value)

·        Particle < 4 µm : 0%

·        Particle < 10 µm : 0.8%

·        Particle < 100 µm : 72%

·        Particle < 500 µm : 100%

Applicant's summary and conclusion

Conclusions:
The particle size distribution of the test substance was determined by laser diffraction according to ISO 13320-2009.
The test item has a median particle size D50 = 85.1 μm.
Executive summary:

The particle size distribution of the test substance was determined by laser diffraction according to ISO13320-2009 in an appropriate dispersive solvent (ethanol).

The MIE diffusion model was used to obtain the volumetric distribution of the test substance.

9 measurements were made during the passage of the powder in the apparatus, the following parameters were determined:

·        D10= 44 µm

·        D90= 152 µm

·        Particle < 4 µm : 0%

·        Particle < 10 µm : 0.8%

·        Particle < 100 µm : 72%

·        Particle < 500 µm : 100%