Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-462-3 | CAS number: 107-10-8
Irritation:- skin: corrosive- eye: corrosive
In a primary skin irritation study n-propylamine caused surface dermatolysis in three out of six animals. Subsequently these sites became dry, hard, and concave. This reaction is characteristic of dry necrosis (Pennwalt 1977; reliability score: 2). Corrosive to highly irritating effects to skin were found in a second study (Smyth et al. 1962; reliability score: 2).
In a primary eye irritation study corrosive effects (corneal opacity) could be observed (Pennwalt 1977; reliability score 2). A further publication confirmed these results (Smyth et al.1962; reliability score: 2).
Due to the effects seen in two older but valid studies, n-propylamine is considered as corrosive to the skin.
Due to the reported corneal injury of the rabbit eye in two studies, n-propylamine is considered as corrosive.
EU classification according to Annex VI of Directive 67/548/EEC: C, R34
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again