Registration Dossier
Registration Dossier
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EC number: 944-553-4 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A study was performed to assess the acute toxicity of the test item toDaphnia magna. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (April 2004) No 202, "Daphniasp., Acute Immobilisation Test" referenced as Method C.2 of Commission Regulation (EC) No. 440/2008.
Results
Chemical analysis of the test preparations at 0 hours showed measured test concentrations to range from 1.40 to 51.1 mg/L. There was no significant change in the measured concentrations at 48 hours other than the exception noted below.
The 56% v/v saturated solution measured concentrations declined by 74% between 0 and48 hours. However, as there was 100% immobilization observed in lower concentrations, the 56% v/v saturated solution was not considered critical to the effect of test item exposure observed in the test and the statistical analysis. Therefore, the results are based on 0-Hour measured test concentrations only.
Exposure ofDaphnia magnato the test item gave the following results based on the 0-Hour measured test concentrations:
Time Point (Hours) |
EC50 |
95% Confidence Limits (mg/L) |
No Observed Effect Concentration (NOEC) (mg/L) |
Lowest Observed Effect Concentration (LOEC) (mg/L) |
48 |
5.5 |
Not determined due to unsuitable nature of data |
4.9 |
9.5 |
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5.5 mg/L
Additional information
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