1,3-Propanediaminium, 2-hydroxy-N1,N1,N1,N3,N3-pentamethyl-N3-[3-[(2-methyl-1-oxo-2-propen-1-yl)amino]propyl]-, chloride (1:2)

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From November 26, 2015 To August 24, 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: isothermal thermogravimetry

Specific details on test material used for the study:

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature (15 °C to 25 °C), in the dark

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
-The test item was applied to the surface of a roughened glass plate in a homogeneous layer.
The test item is solid – bobbled paste, due to test item physical state test item was applied directly to the surface of a roughened glass plate.

Key result

Remarks on result:

not determinable

Key result

Transition / decomposition:

yes

Transition temp.:

> 230 °C

Remarks on result:

not determinable

During the test, the colour of the test item changed from beige to dark brown.

The weight loss was not reproducible in the temperature range used. Higher temperatures cannot be used to determine the test item vapour pressure due to its decomposition at 240°C. Therefore, the decomposition occurred before a rate of evaporation was measured; hence an accurate measure of vapour pressure by this method was not possible.

Based on the limited data the vapour pressure of the test item cannot be determined. So we compared the test item vapour pressure data with the data of the reference items: Hexachlorobenzene and Chrysene.

The vapour pressure of the test item was estimated to be in the range from 10^-7 Pa to 10^-10 Pa.

Conclusions:

Due to very low and unrepeatable weight loss at lower temperatures, and decomposition at higher temperatures (240°C), the vapour pressure of the test item at 20°C (293K) cannot be determined with sufficient accuracy.
The vapour pressure of the test item was estimated to be in the range from 10-7 Pa to 10-10 Pa, compared to the vapour pressure of the used reference items (Hexachlorobenzene and Chrysene).

Executive summary:

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of the test item.

Below 100°C, the weight loss of the test item was not reproducible. The method was adapted and used between 100°C and 230°C.

The color of the test item changed from beige to dark brown in the temperature range from 20°C to 230°C indicating decomposition at higher temperatures.

Due to very low and unrepeatable weight loss at lower temperatures, and decomposition at higher temperatures (240°C), the vapour pressure of the test item at 20°C (293K) cannot be determined with sufficient accuracy according to the following criteria described in the guidelines used (EU A.4 and OCED 104).

# the test item do not decompose under the condition of the test

# the determination of vapour pressure should be performed for the three or more different temperatures

# the measurements should be reproducible

Therefore, the vapour pressure of the test item was estimated to be in the range from 10^-7 Pa to 10^-10 Pa, compared to the vapour pressure of the used reference items (Hexachlorobenzene and Chrysene).

Description of key information

The vapour pressure of the test item was determined according to recognized guideline (EU Method A.4 and OECD guideline 104) and under GLP.

No deviation from the guideline was observed during the test.

Additional information

Due to very low and unrepeatable weight loss at lower temperatures, and apparent decomposition at higher temperatures, the vapour pressure of the test item at 20°C (293K) cannot be determined with sufficient accuracy.

Therefore, the test item vapour pressure was estimated to be in the range from 10^-7Pa to 10^-10Pa, compared to the vapour pressure of the used reference items (Hexachlorobenzene and Chrysene).