Sulfuric Acid, waste gas washing, copper smelting

Acute Toxicity: inhalation

Administrative data

Endpoint:

acute toxicity: inhalation

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no GLP (but other Quality Assurance); software

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2010

Materials and methods

Principles of method if other than guideline:

Acute (inhalation) toxicity of the UVCB was determined by classifying based on Mixture Toxicity rules from EU CLP (summation and/or additivity of classified components to derive hazard class), and back calculation to the corresponding Acute (inhalation) toxicity criteria.

GLP compliance:

no

Remarks:

equivalent Quality Assurance

Test type:

other: CLP calculation software

Test material

Test material information

Constituent 1

Reference substance name:

sulfuric acid hydrate

EC Number:

922-670-1

IUPAC Name:

sulfuric acid hydrate

Details on test material:

Worst case (max across industry), as from IUCLID section 1.2, see IUCLID section 1.4 for company specific elemental composition, and representative samples for mineralogical information (+ section 4.23)

Results and discussion

Effect levels

Dose descriptor:

other:

Effect level:

> 10 - <= 20 other: ATE (mg/l)

Based on:

dissolved

Exp. duration:

4 h

Remarks on result:

other: prediction (vapours)

Any other information on results incl. tables

The calculated classification via Additivity method (lower Tier Arche CLP Tool) resulted in a classification "Acute (inhalation) Category 4 H332" (driven mainly by Arsenic) for the UVCB substance (toxicity of all metal constituents > 1% w/w is known, from 1st ATP CLP + all assessed metals).

Based on this result, the related criteria provided the estimated value for acute (inhalation, vapours) toxicity: 10 < Acute Toxicity Estimate < or equal 20 (mg/l)

Applicant's summary and conclusion

Interpretation of results:

Toxicity Category IV

Remarks:

Migrated information Criteria used for interpretation of results: other: EU CLP mixture toxicity rules

Conclusions:

Good quality study that can be used to predict a ATE of the UVCB substance. Note: toxicities of constituents/species as of 1st ATP CLP + assessed metals

Executive summary:

The study provided a conservative estimate of the Acute (inhalation) toxicity, derived on basis of the Classification outcome (Mixture toxicity rules, acute inhalation toxicity category 4) from a (worst case, max across industry) Sulfuric acid, waste gas cooling and cleaning, copper smelting as defined in IUCLID section 1.2/1.4/4.23. The result is applicable to all Sulfuric acid, waste gas cooling and cleaning, copper smelting

that fall under the defined concentration ranges (IUCLID section 1.2).