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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The 48-hour EC50 value of 873 mg/L for ethyl 3-ethoxypropanoate is the geometric mean of two 48-hour EC50 values taken from two valid exposure studies with Daphnia magna.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
873 mg/L

Additional information

Two acute toxicity tests were listed for this endpoint. One study was assigned a Klimish score of 1, while the other study was assigned a Klimish score of 2 based on the lack of analytical measures of test solution concentrations. Both studies were conducted with Daphnia magna, and the 48-hour EC50 values (based on immobility) were reported as 785 and 970 mg/L. In accordance with ECHA guidance (R.10.2.2), the geometric mean of the toxicity endpoints, if within an order of magnitude, can be used to calculate a species value for a given endpoint. Thus, the key parameter for the acute invertebrate endpoint was the LC50 value of 873 mg/L, which was the geometric mean of two 48-hour EC50 values (785 and 970 mg/L) reported for ethyl 3-ethoxypropanoate in tests with Daphnia magna.