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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September-October 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
equivalent or similar to
Guideline:
OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
Version / remarks:
2001
Deviations:
not applicable
Principles of method if other than guideline:
OECD 29 (2001) is a guidance document on transformation/dissolution of metals and metal compounds in aqueous media. The protocol included in the guidance is being considered for formal validation.

An experiment based on the 'dissolution screening test - sparingly soluble metal compounds' as described in OECD 29 (2001) was performed. Nominal substance concentrations of 1 mg/L were agitated for 24 hours (at pH 1) or 28 days (at pH 7) with aqueous dissolution media. After centrifugation, a sample from each test solution was analysed for bismuth by ICP analysis.
GLP compliance:
no
Type of method:
other: dissolution screening test
Water solubility:
< 8 µg/L
Conc. based on:
other: Bismuth
Loading of aqueous phase:
1 mg/L
Incubation duration:
28 d
pH:
7
Remarks on result:
other: ambient temp.
Water solubility:
154 µg/L
Conc. based on:
other: Bismuth
Loading of aqueous phase:
1 mg/L
Incubation duration:
24 h
pH:
1
Remarks on result:
other: ambient temp.
Key result
Water solubility:
< 0.1 mg/L
Remarks on result:
other: overall conclusion

Table: Test conditions

pH

Solution

Start of agitation

End of agitation*

 

 

pH

Temp.

[°C]

pH

Temp.

[°C

 

 

 

 

 

 

1

Test sol. 1

 

 

1.04

22.6

 

Test sol 2

 

 

1.05

22.5

 

Test sol. 3

 

 

1.05

22.4

 

Blank

1.04

21.2

1.06

21.1

 

 

 

 

 

 

7

Test sol. 1

 

 

7.00

23.9

 

Test sol 2

 

 

7.02

23.9

 

Test sol. 3

 

 

7.01

23.8

 

Blank

6.98

23.7

7.28

23.8

 

 

 

 

 

 

* 24 h for pH 1, 28 days for pH 7

Table: Analytical results

pH

 Solution

Nominal concentration of

BiOI0.6 Br0.4 [mg/L]

Concentration analysed of dissolved Bi

[µg/L]

Calculated * concentration of dissolved

BiOI0.6 Br0.4

[µg/L]

Mean conc. of dissolved

BiOI0.6 Br0.4

[µg/L]

 

 

 

 

 

 

1

Test sol. 1

1.21

97

155

154

 

Test sol. 2

1.17

100

159

 

 

Test sol. 3

1.15

93

148

 

 

Blank

-

<5

 

 

 

 

 

 

 

 

7

Test sol. 1

0.99

<5

<8

<8

 

Test sol. 2

1.01

<5

<8

 

 

Test sol. 3

0.98

<5

<8

 

 

Blank

-

<5

 

 

* Using the molecular weight fraction of bismuth of 62.7%.

Conclusions:
An experiment based on the 'dissolution screening test - sparingly soluble metal compounds' as described in OECD 29 (2001) was performed. Nominal substance concentrations of 1 mg/L were agitated for 24 hours (at pH 1) or 28 days (at pH 7) with aqueous dissolution media. After centrifugation, a sample from each test solution was analysed for bismuth by ICP analysis. At pH 7, the amount of (dissolved and/or dissociated) bismuth is below the limit of detection. This corresponds with a substance concentration of < 8 µg/L. At pH 1, very small amounts of (dissolved and/or dissociated) bismuth were measured corresponding with a substance concentration of 154 µg/L. Based on all results the water solubility of the substance was concluded to be very low (< 0.1 mg/L).

Description of key information

The water solubility of the substance was visually determined to be < 1 mg/L at 20°C.
From the results of an experiment based on the 'dissolution screening test - sparingly soluble metal compounds' as described in OECD 29 (2001) it can be concluded that the water solubility of the substance is very low. At pH 7, the amount of (dissolved and/or dissociated) bismuth is below the limit of detection. This corresponds with a substance concentration of < 8 µg/L. At pH 1, very small amounts of (dissolved and/or dissociated) bismuth were measured corresponding with a substance concentration of 154 µg/L.

Key value for chemical safety assessment

Additional information

The water solubility of 3 different batches of the substance was visually determined. With all 3 batches, the same result was obtained.