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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from modelling database.
Qualifier:
according to
Guideline:
other: As Mention Below
Principles of method if other than guideline:
To determine the partition coefficient of 4-methylpiperazin1-amine
GLP compliance:
not specified
Type of method:
other: estimation
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Name of test material : 4-methylpiperazin1-amine
Molecular formula : C5H13N3
Molecular weight : 115.179 g/mol
Physical appearence : Liquid
Smiles notation : N1(CCN(CC1)C)N
InChl : 1S/C5H13N3/c1-7-2-4-8(6)5-3-7/h2-6H2,1H3
Key result
Type:
log Pow
Partition coefficient:
-1.61
Remarks on result:
other: other details not available
Conclusions:
Octanol water partition coefficient (Log Pow) of 4-methylpiperazin1-amine estimated is -1.61.
Executive summary:

The Octanol water Partition coefficient (Log Pow) of 4-methylpiperazin1-amine( CAS no. 6928 -85 -4) predicted from EPI Suite and Danish QSAR is -1.61. This value suggests that this chemical is hydrophilic in nature.

Description of key information

The Octanol water Partition coefficient (Log Pow) of 4-methylpiperazin1-amine( CAS no. 6928 -85 -4) predicted from EPI Suite and Danish QSAR is -1.61. This value suggests that this chemical is hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.61
at the temperature of:
25 °C

Additional information

The Octanol water Partition coefficient (Log Pow) of 4-methylpiperazin1-amine( CAS no. 6928 -85 -4) predicted from EPI Suite and Danish QSAR is -1.61. This value suggests that this chemical is hydrophilic in nature.