Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
May 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Well documented, recent guideline study.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.03
Temp.:
23 °C
pH:
>= 6 - <= 8

Any other information on results incl. tables

Results in detail:

determ. no.

stock solution

 

 

[ml]

water

 

 

[ml]

test substance conc. in n-octanol phase

[mg/l]

test substance conc. in water phase

[mg/l]

ratio water : n-octanol

log Pow

A1

10

20

635.2

4.2

2 : 1

2.18

A2

10

20

630.5

4.5

2 : 1

2.15

B1

20

20

626.5

5.8

1 : 1

2.03

B2

20

20

633.7

5.6

1 : 1

2.06

C1

40

20

627.9

8.4

1 : 2

1.88

C2

40

20

625.8

8.3

1 : 2

1.88

mean

--

--

--

--

--

2.03

Recovery rate of test substance:            

determ. no.

test substance in stock solution

[mg]

test substance in n-octanol phase

[mg]

test substance in water phase

[mg]

sum

 

 

[mg]

recovery rate

 

 

[%]

A1

6.43

6.35

0.08

6.44

100

A2

6.43

6.30

0.09

6.39

99

B1

12.86

12.53

0.12

12.65

98

B2

12.896

12.67

0.11

12.78

99

C1

25.72

25.12

0.17

25.29

98

C2

25.72

25.03

0.17

25.20

98

Applicant's summary and conclusion