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Environmental fate & pathways

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In accordance with REACH Annex XI, the "Hydrolysis as a function of pH" does not need to be conducted as the test is scientifically unjustified respective technically not feasable. The guanidine ion is expected to have such a long hydrolysis half-life at environmentally relevant pH that the measurement is not feasable. This is concluded from abiotic biodegradation control with river water (Mitchel, Chemosphere, 1987).


Guanidine Thiocyanate was proven to be inherently biodegradable in an OECD guideline 302B study.

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