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Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2021-03-01 - 2021-04-30
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
Type of method:
flask method
Specific details on test material used for the study:
Lot 2103311210
Key result
Water solubility:
ca. 1 562 g/L
Conc. based on:
test mat.
Incubation duration:
> 24 - <= 120 h
20 °C
ca. 6.2
The mean watersolubility of Guanidinium thiocyanate is 1562 g/L at 20 +/- 0.5 °C.
The pH of the satureted solution is 6.2.
Executive summary:

The solubility of Guanidinium Thiocyanate was determined in water at a temperature of 20 ± 0.5 °C according to OECD guideline 105 (Shake Flask) with restrictions.
The results are presented in the following table:

Solubility of guanidinium thiocyanate in water at 20 ± 0.5 °C

Determined pH6.2
Mean solubility [g/L]1562

The repeated samplings indicate the required reproducibility (relative standard deviation below 15%).

Description of key information

The water solubility of Guanidine thiocyanate was measured to be 1562 g/L at 25 °C.

Key value for chemical safety assessment

Water solubility:
1 562 g/L
at the temperature of:
20 °C

Additional information