Registration Dossier
Registration Dossier
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EC number: 453-460-3 | CAS number: -
Appearance / physical state / colour
Administrative data
Link to relevant study record(s)
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 November 2015 to 29 January 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Observations associated with GLP guideline studies.
- Qualifier:
- no guideline required
- GLP compliance:
- yes (incl. QA statement)
- Physical state at 20°C and 1013 hPa:
- liquid
- Key result
- Form:
- liquid
- Colour:
- Colourless
- Odour:
- other: no data
- Substance type:
- organic
- Conclusions:
- The test item was observed to be a clear, colourless, liquid.
- Executive summary:
The test item was observed to be a clear, colourless, liquid during performance of GLP guideline studies.
- Endpoint:
- appearance / physical state / colour
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 06 November 2012 to 18 January 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
- Qualifier:
- no guideline followed
- GLP compliance:
- yes
- Physical state at 20°C and 1013 hPa:
- liquid
- Form:
- not specified
- Colour:
- clear, colourless
- Odour:
- other: no odour reported
- Substance type:
- organic
- Conclusions:
- The substance is a clear, colourless liquid with no reported odour
- Executive summary:
The substance is a clear, colourless liquid with no reported odour.
- Endpoint:
- appearance / physical state / colour
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- To register EC453-460-3 under REACH program, a read-across approach for fulfillment of the endpoints has been adopted. EC453-460-3 is an aliphatic ester and fits the description of polyol esters category in HPV program (High Production Volume, US-EPA). The distinguishing feature of polyol esters category is that the fatty acids were linked to one or more of the multiple hydroxyl groups present in the polyol (alcohol portion of ester). The focus of this correspondence is to support read across to EC613-848-7 (target) which provided key studies to determine hazard profile of EC453-460-3 (target), published information on other structurally analogous polyol esters were served as supporting evidence.
- Reason / purpose for cross-reference:
- read-across source
- Physical state at 20°C and 1013 hPa:
- liquid
- Form:
- not specified
- Colour:
- clear, colourless
- Odour:
- other: no odour reported
- Substance type:
- organic
- Conclusions:
- The substance is a clear, colourless liquid with no reported odour
- Executive summary:
The substance is a clear, colourless liquid with no reported odour.
Referenceopen allclose all
Description of key information
The test item was observed to be a clear, colourless, liquid.
Key value for chemical safety assessment
- Physical state at 20°C and 1013 hPa:
- liquid
Additional information
The test item was observed to be a clear, colourless, liquid during performance of GLP guideline studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
