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EC number: 811-367-9 | CAS number: 11073-79-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 09 - December 18, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 4 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 6.5
- Details on results:
- Individual results
Preliminary visual estimation of the water solubility
Three preliminary tests were carried out with specified amounts of the test item and 100 ml and 500 ml distilled water, respectively. After each addition of an amount of water, the mixture was stirred for at least 24 hours, and visually checked for any undissolved particles (see Table 1).
The solubility of the test item in water was found to be below 9.8 mg/l (without correction for the purity). In this range the water solubility of test items should be determined with the column elution method. However as the present test item Gadolinium Zirkonat is an inorganic substance the suitable method according to ECHA guidance R.7a is the flask method with two loading rates.
Flask method
The flask method was performed as described above. The data for the evaluation are given in Table 2. After the equilibration time a small amount of precipitate was observed in the flasks of the experiments A – C (see Table 2) and considerable precipitate in the flasks of the experiments E - G (see Table 3). The water solubility was calculated under assumption of the molecular formula and the molecular weight given above.
The calculated water solubility for gadolinium was deviating from the calculated water solubility for zirconium. This was most likely caused by a different chemical behaviour of the elements gadolinium and zirconium. It was assumed that zirconium formed insoluble compounds during the stirring time.
The water solubility experiments showed no significant dependence on the loading rate but a dependence on the stirring time. Therefore the experiment with a loading rate of 0.1 g/l was repeated with extended stirring times. The results are summarised in Table 4.
The water solubility of the test item Gadolinium Zirkonat showed an unusual behaviour that was most likely caused by the chemical nature of the test item. As a conservative approach the highest measured water solubility was taken as final result.
The water solubility of the test item at 20 °C was determined to be 4.0 mg/l. - Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the test item at 20 °C was determined to be 4.0 mg/l. - Executive summary:
In a study according to OECD Guideline 105 the water solubility of gadolinium zirconium oxide was determined (flask method).
The water solubility at a temperature of 20 °C of the test item gadolinium zirconium oxide showed an unusual behaviour: the calculated water solubility for gadolinium was deviating from the calculated water solubility for zirconium. This was most likely caused by a different chemical behaviour of the elements gadolinium and zirconium. It was assumed that zirconium formed insoluble compounds during the stirring time. As a conservative approach the highest measured water solubility was taken as final result. It was found to be: cS= 4.0 mg/l
Reference
Table 1: Results of the preliminary visual estimation of the water solubility
Amount of the test item / mg |
Total volume / ml |
Appearance of mixture |
9.9 |
100 |
undissolved |
12.2 |
500 |
undissolved |
4.9 |
500 |
undissolved |
Table 2: Water solubility experiments A - D, loading rate 0.1 g/l
Experiment |
A |
B |
C |
Blank experiment (D) |
Amount of test item / mg |
5.9 |
5.9 |
6.1 |
-- |
Amount of distilled water / ml |
50 |
50 |
50 |
50 |
Stirring time at 30 °C / h |
24 |
48 |
72 |
72 |
pH at 23 °C |
6.5 |
6.4 |
6.5 |
6.2 |
Measured concentration |
0.01 |
0.02 |
2.1 |
< 0.01 |
Water solubility based on gadolinium concentration / mg/l |
0.02 |
0.04 |
4.0 |
< 0.02 |
Measured concentration |
< 0.02 |
< 0.02 |
< 0.02 |
< 0.02 |
Water solubility based on zirconium concentration / mg/l |
< 0.07 |
< 0.07 |
< 0.07 |
<0.07 |
Table 3: Water solubility experiments E - H, loading rate 1.0 g/l
Experiment |
E |
F |
G |
Blank experiment (H) |
Amount of test item / mg |
53.5 |
52.6 |
53.4 |
-- |
Amount of distilled water / ml |
50 |
50 |
50 |
50 |
Stirring time at 30 °C / h |
24 |
48 |
72 |
72 |
pH at 23 °C |
6.8 |
6.7 |
6.7 |
6.3 |
Measured concentration |
< 0.01 |
0.20 |
0.56 |
< 0.01 |
Water solubility based on gadolinium concentration / mg/l |
< 0.02 |
0.38 |
1.1 |
< 0.02 |
Measured concentration |
< 0.02 |
< 0.02 |
< 0.02 |
< 0.02 |
Water solubility based on zirconium concentration / mg/l |
< 0.07 |
< 0.07 |
< 0.07 |
<0.07 |
Table 4: Water solubility experiments I - L, loading rate 0.1 g/l
Experiment |
I |
J |
K |
Blank experiment (L) |
Amount of test item / mg |
5.7 |
5.3 |
5.5 |
-- |
Amount of distilled water / ml |
50 |
50 |
50 |
50 |
Stirring time at 30 °C / h |
72 |
96 |
120 |
120 |
pH at 23 °C |
6.2 |
6.3 |
6.3 |
5.9 |
Measured concentration |
< 0.01 |
< 0.01 |
< 0.01 |
< 0.01 |
Water solubility based on gadolinium concentration / mg/l |
< 0.02 |
< 0.02 |
< 0.02 |
< 0.02 |
Measured concentration |
< 0.02 |
< 0.02 |
< 0.02 |
< 0.02 |
Water solubility based on zirconium concentration / mg/l |
< 0.07 |
< 0.07 |
< 0.07 |
<0.07 |
Description of key information
The water solubility of gadolinium zirconium oxide is 4.0 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 4 mg/L
- at the temperature of:
- 20 °C
Additional information
In a study according to OECD Guideline 105 the water solubility of gadolinium zirconium oxide was determined (flask method).
The water solubility at a temperature of 20 °C of the test item gadolinium zirconium oxide showed an unusual behaviour: the calculated water solubility for gadolinium was deviating from the calculated water solubility for zirconium. This was most likely caused by a different chemical behaviour of the elements gadolinium and zirconium. It was assumed that zirconium formed insoluble compounds during the stirring time. As a conservative approach the highest measured water solubility was taken as final result. It was found to be: cS= 4.0 mg/l
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