Registration Dossier
Registration Dossier
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EC number: 218-817-8 | CAS number: 2243-62-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: No OECD guideline or GLP defined. Insufficient data documentation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
Materials and methods
- Principles of method if other than guideline:
- other: Akute toxicity, s.c., rat
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- 1,5-naphthylenediamine
- EC Number:
- 218-817-8
- EC Name:
- 1,5-naphthylenediamine
- Cas Number:
- 2243-62-1
- Molecular formula:
- C10H10N2
- IUPAC Name:
- 1,5-naphthylenediamine
- Details on test material:
- IUCLID4 Test substance: other TS: purity 98.7 %
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- body weight 120-140g
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- water
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 1 563 mg/kg bw
- Mortality:
- no detailed information given, exept LD50 = 1563 mg/kg bw.
- Clinical signs:
- no data
- Body weight:
- 120-140g
- Gross pathology:
- no data
- Other findings:
- no data
Any other information on results incl. tables
no data
Applicant's summary and conclusion
- Executive summary:
Female Wistar rats (120 -140 g; no.of animals unknown) were injected s.c. once with the test substance suspension.
The LD 50 was 1563 mg/kg bw.
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