Registration Dossier

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other: Biomonitoring study: IUCLID 4 migrated data set
Rationale for reliability incl. deficiencies:
other: Biomonitoring study.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Biomonitoring of Urinary Aromatic Amines and Arylamine Haemoglobin Adducts in Exposed Workers and Non-Exposed Control Persons
Author:
Riffelmann M. et al.
Year:
1995
Bibliographic source:
Dokladi-Bulgarskata Akademiia Naukite 48, 79-82 (1995)
Reference Type:
publication
Title:
Unnamed
Year:
1995

Materials and methods

Study type:
other: study with workers exposed to arylamines; Biomonitoring
Principles of method if other than guideline:
method: other: Biomonitoring
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1,5-naphthylenediamine
EC Number:
218-817-8
EC Name:
1,5-naphthylenediamine
Cas Number:
2243-62-1
Molecular formula:
C10H10N2
IUPAC Name:
1,5-naphthylenediamine
Details on test material:
no data

Method

Type of population:
occupational
Ethical approval:
not specified
Route of exposure:
other: Biomonitoring
Reason of exposure:
intentional, occupational
Exposure assessment:
not specified

Results and discussion

Clinical signs:
Biomonitoring study: IUCLID 4 migrated data set

Any other information on results incl. tables

RM-Freetext:
1,5-naphthylenediamine was shown in the urine of workers
exposed to aromatic amines.

Applicant's summary and conclusion

Executive summary:

In a biomonitoring study 1,5-naphthylenediamine was shown in the urine of workers exposed to aromatic amines.