Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 228-055-8 | CAS number: 6104-30-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: long-term
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Since for N,N''-(isobutylidene)diurea (CAS 6104-30-9) the log Kow is < 3, no persistence and thus no long-term exposure of sediment organisms is expected and no toxicity was determined in acute aquatic toxicity test, no toxicity study with sediment organisms is needed
Key value for chemical safety assessment
Additional information
N,N''-(isobutylidene)diurea (CAS 6104-30-9) is characterized by a log Kow < 3 (log Kow = -0.903 at 23°C). According to chapter R. 7b of the ‘Guidance on information requirements and chemical safety assessment' (ECHA, 2017) a log Kow of 3 is defined as a trigger value for a sediment assessment. The log Kow of N,N''-(isobutylidene)diurea (CAS 6104-30-9) is -0.903 and thus < 3. Therefore, no adsorbtion to sediment is expected and no sediment testing is needed.
Furthermore, the substance is readily biodegradable and thus expected to be extensively removed from water in sewage treatment plants. As mentioned in the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b (ECHA, 2017), the ready biodegradability of a substance can be an indication of rapid and ultimate degradation in most environments, including biological sewage treatment plants (STP). Due to the ready biodegradation, it is assumed that the discharged concentration of N,N''-(isobutylidene)diurea (CAS 6104-30-9) in the effluent of conventional STPs is negligible. Thus, insignificant release into the aqueous compartment and thus also in the sediment compartment is expected. Furthermore, the substance is expected to undergo rapid and ultimate degradation if released into the water compartment. Thus, persistence and thus long-term exposure of sediment organisms is not expected due to the ready biodegradability of the substance.
Moreover, the available acute aquatic toxicity tests with freshwater organisms demonstrated that the substance show no toxicity to aquatic organisms. Thus, toxicity is also not expected for sediment organisms.
In conclusion, since for N,N''-(isobutylidene)diurea (CAS 6104-30-9) the log Kow is < 3, no persistence and thus no long-term exposure of sediment organisms is expected and no toxicity was determined in acute aquatic toxicity test, no toxicity study with sediment organisms is needed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
