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EC number: 214-968-9 | CAS number: 1229-55-6
Table: Primary Dermal Irritation of Solvent Red 1
Initial Body Weight (kg)
**= after test article application
R= test site stained red
Primary Irritation Score = (A+B+C+D+E+F+G+H+I+J+K+L+M+N+O+P)/8
Primary Irritation Score = 0.0
The primary dermal irritation of Solvent Red 1 was assessed in rabbits. The backs of six New Zealand White (NZW) rabbits (three of each sex) were closely clipped 24 hours before dosing. Each rabbit received a dose of 0.5ml Solvent Red 1 on two intact sites and two abraded sites (the right anterior and the left posterior were abraded). After 24 hours of exposure, the wrappings and patches were removed and sites wiped off with gauze sponges moistened with water. Sites were scored at 24 and 72 hours after application using the method of Draize (1979).Each animal was weighed prior to application of each test article. All animals were observed at least once daily for mortality and obvious toxic signs.
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