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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment: mixture of 18 toxicants: With respect to 1,2,3 trichlorobenzene alone the publication provides no information.

Data source

Reference
Title:
No information
Author:
Foster WG et al. (2004), Mammary gland morphology in Sprague-Dawley rats following treatmet with an organochlorine Mixture in utero and neonatatal genestein. Toxicol. Sci. 77, 91-100

Materials and methods

Type of study / information:
Type: other
Principles of method if other than guideline:
Migrated dataset. Pregnant female rats were exposed in utero once a day from day 9- 16 of gestation to a mixture of 18 toxicants (1x the acceptable daily intake) to examine the effect on mammary gland histology. One component of the mixture was 1,2,3-trichlorobenzene. Only mild histological changes were found in mammary glands of the rats.

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Migrated dataset

Applicant's summary and conclusion