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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- , see "prinicples of method if other than guideline"
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- yes
- Remarks:
- , see "prinicples of method if other than guideline"
- Principles of method if other than guideline:
- The concentration of methanol in the solvent control was higher than demanded in
the guideline. As no significant immobilisation occurred during the test, this deviation
was stated as uncritical. - GLP compliance:
- yes (incl. QA statement)
Test material
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 8 µg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks on result:
- other: (limit of water solubility)
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 8 µg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks on result:
- other: (limit of water solubility)
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 8 µg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks on result:
- other: (limit of water solubility)
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 8 µg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks on result:
- other: (limit of water solubility)
Any other information on results incl. tables
Purpose of the Study
This study was per-formed in order to evaluate the toxic potential of Sa 163 / SAT-No.
080003 towards freshwater shrimp, using the species Daphnia magna. Daphnia magna
SIRAUS, which belongs to the family of crustacea, was chosen in the guideline as a typical
paft of zoo-plancton. sponsor's intent: notification according to REACH.
Phases of the Study
Study Director of the whole study was Dipl. Ing. Manfred Muckle, Head of Deparlment
Ecotoxicology of LAUS GmbH. The person responsible for the quality assurance of the
study was Jutta Paulus, Head of Quality Assurance Unit of LAUS GmbH.
The study was divided in the following phases:
Phase 1: (Performance of the Ecotoxicity Study)
Phase 1 of the study was peformed at the test facility LAUS GmbH.
Phase 1 means the per-formance of the toxicity study against Daphnia magna, sample
preparation and shipment of the samples for phase 2. Principal Investigator for phase 1
was Mr. Muckle. For the quality assurance of this phase, Ms. Paulus was responsible.
Phase 2: Analysis of the Test Solutions
Phase 2 of the study was peformed at the test site Henkel AG & co. KGaA.
Phase 2 means the analytical determination of the test item in the test solutions. principal
Investigator for phase 2 was Dr. Matthias Frischmann. For the quality assurance of this
phase, Dr. Barbara Wiecken was responsible.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- All validity criteria were met. For the estimation of the EC50 of the positive control, the fit
showed sufficient statistical correspondence of the data with the dose-response-equation.
The 24h-EC50i of potassium dichromate was determined as 1.6 mg/L, lying within the demanded
range of 0.6 - 1.7 mg/L.
No significant toxicity was observed in control, solvent control and treatment.
The analytical determinations showed strong scattering single values and the measured
concentrations were above the calibrated working range. Therefore, the three retained replicates
of each sample were analysed, too, using a different, freshly calibrated working
range. The measurement of the retained samples showed also scattering single values
and most values were lower than the calibrated working range. Therefore, the limit of water
solubility was used as effective concentration for determination of the results.
As the theoretical concentration in the aquaria was about twice as high as the limit of water
solubility, un-dissolved test item was accumulated at the surface of the aqueous solution.
Therefore, the measured values were much higher than expected. As there was no toxicity
observed and the concentration exceeded the limit of water solubility during the test, this
was stated as uncritical and the result of the test is considered valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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