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EC number: 300-340-2 | CAS number: 93925-38-3
Primary irritation Score: 0.34/4=0.09
Method and Material
Six New Zealand White rabbits were clipped and then one side of the back was abraded to penetrate the stratum corneum with the other side kept intact. A 0.5 mL portion of the test material was applied to an abraded and an intact skin site of the same rabbit. A gauze patch was placed over each application site and an impervious material was wrapped around the trunk of the animal to hold the patches. The wrapping was removed after 24 hours. Treated areas were examined for erythema and edema using the Draize method of scoring at 24 and 72 hours.
Only one rabbit exhibited very slight erythema at the 24 hour observation. There was no other irritation effect noted in any other rabbits at the 24 hour observation and all rabbits appeared normal at the 72 hour observation. All observed effects were reversed by the 72 -hour observation.
In accordance with EU CLP Regulation (EC) No. 1272/2008, classification of this substance is not required for skin irritation.
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