Registration Dossier
Registration Dossier
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EC number: 225-795-3 | CAS number: 5081-87-8
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 September - 03 December 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Goods, Part III, Test N.4: “Test Method for Self-Heating Substances" (2009)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3-(2-chloroethyl)(1H,3H)quinazoline-2,4-dione
- EC Number:
- 225-795-3
- EC Name:
- 3-(2-chloroethyl)(1H,3H)quinazoline-2,4-dione
- Cas Number:
- 5081-87-8
- Molecular formula:
- C10H9ClN2O2
- IUPAC Name:
- 3-(2-CHLOROETHYL)QUINAZOLINE-2,4(1H,3H)-DIONE
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study report): JNJ-232726-AAA (T001201)
- Physical state: solid
- Appearance: off-white powder
- Analytical purity: >99.16%
- Batch n°: I15CB1185
- Expiration date: 15 March 2017
- Storage condition: at room temperature
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Key result
- Remarks on result:
- no self-ignition observed up to the melting point
Any other information on results incl. tables
No endothermic or exothermic effect of the test item was observed between 20°C and 195°C (which is the melting temperature of the test item). It demonstrated that the test item is not self-ignitable.
After the experiment, the test item had turned into a black charred residue and was collected in a container that was placed below the cube. It indicated that the test item had molten, decomposed and/or reacted during the experiment.
Main test
Based on the results of the preliminary test, the main study according to UN N.4 was not performed.
Applicant's summary and conclusion
- Conclusions:
- Based on the results of the EC A.16 test performed, the test item is considered ‘not self-ignitable’. Because there were no indications of self-heating properties, the test item was considered 'not self-heating' and the main study according to UN N.4 was not performed.
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