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EC number: 219-264-5 | CAS number: 2398-37-0
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment
From BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for 1-bromo-3-methoxybenzene is 46.37 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that 1-bromo-3-methoxybenzene is not expected to bio accumulate in the food chain.
Additional information
Bioaccumulation: aquatic / sediment
Four prediction reports from validated models for bioaccumulation in aquatic environment endpoint of test chemical 1-bromo-3-methoxybenzene (Cas no. 2398-37-0) were reviewed as follows:
First prediction done using BCFBAF (v3.01) model of EPI suite, estimated bio concentration factor (BCF) for 1-bromo-3-methoxybenzene to be 46.37 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that 1-bromo-3-methoxybenzene is not expected to bio accumulate in the food chain.
Another predicted model PBT profiler; 2017 indicated the Bioaccumulation factor (BCF) to be 46 at 25 deg.C for test chemical 1-bromo-3-methoxybenzene. Based on the BCF concentration it is concluded that the test chemical 1-bromo-3-methoxybenzene is non bioaccumulative in nature as it does not exceed the BCF criteria of 2000.
From Scifinder database, the Bioconcentration factor (BCF) for target chemical 1-bromo-3-methoxybenzene was predicted to be 122 at pH 1-10 and temperature 25 deg.C. Based on the BCF concentration at all range of pH it is concluded that the test chemical 1-bromo-3-methoxybenzene is non bioaccumulative in nature as it does not exceed the BCF criteria of 2000.
Another estimation from ACD/PhysChem Suite of Chemspider suggest the Bioconcentration factor (BCF) for target chemical 1-bromo-3-methoxybenzene to be 122.81 at pH 5.5 and 7.4 at temperature 25 deg.C. Based on the BCF concentration at two different pH, it an be concluded that the test chemical 1-bromo-3-methoxybenzene is non bioaccumulative in nature as it does not exceed the BCF criteria of 2000.
All reports from reliable prediction models indicate the Bioaccumulation value (BCF) to be in the range 46 -122.81 for target chemical 1-bromo-3-methoxybenzene. Thus, it can be concluded that the test substance 1-bromo-3-methoxybenzene (Cas no. 2398-37-0) is non bioaccumulative in aquatic environment as it does not exceed the BCF criteria of 2000.
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